Welcome to
Cheryl Conrad’s research webpage. Scientific advances in this lab are
accomplished through the hard work and dedication of many individuals:
graduate students, technicians, undergraduate research volunteers,
honor’s students, and collaborations with other faculty and scientists.
The
purpose of our research is to understand the consequences of chronic
stress on the brain and behavior. Chronic stress has far reaching
effects, from exacerbating conditions that include AIDS, Alzheimer’s
disease, depression, obesity, and autoimmune disorders, to triggering
drug relapse. The studies performed in our lab specifically investigate
the morphological and functional changes in the hippocampus following
chronic stress. In rodents, chronic stress makes the hippocampus
vulnerable to brain injury and cognitive dysfunction. A highly
consistent change in the hippocampus following chronic stress is the
selective pruning of dendrites, a specialized region of neurons that
facilitates communication among neurons. Thus, our studies investigate
the mechanism(s) that underlie changes in hippocampal dendritic
morphology following chronic stress to facilitate treatment strategies
for cognitive improvement.